KNYGA Jiri Mestecky Immunology of Milk and the Neonate

Session I: Breastfeeding and Maternal-Neonatal Interactions. Epidemiological Aspects of Breastfeeding.- Characteristics of Human Milk Antibodies and Their Effect in Relation to the Epidemiology of Breastfeeding and Infections in a Developing Country.- T Cell Development in the Fetus and Neonate.- Growth Factors and the Development of Neonatal Host Defense.- Session II: Development of the Neonatal Immune System.- Amniotic Fluid: The First Feeding of Mucosal Immune Factors.- Ontogeny of the Secretory IgA System in Humans.- IgA-Secreting Cells in the Blood of Premature and Term Infants: Normal Development and Effect of Intrauterine Infections.- Development of T Cells with Memory Phenotype in Infancy.- The Effect of Human Milk, Protein-Fortified Human Milk and Formula on Immunologic Factors of Newborn Infants.- Ontogeny of the Mucosal Immune Response in Children.- Session III: Function of Cytokines in the Development of the Immune System.- Are Cytokines in Human Milk?.- The Developing Gastrointestinal Tract and Milk-Borne Epidermal Growth Factor.- Growth Factor Signal Transduction in Human Intestinal Cells.- Role of IL-6 in Human Antigen-Specific and Polyclonal IgA Responses.- Immunological Properties and Differentiation Potential of Human Colostral Lymphocytes of B Cell Lineage.- Session IV: Innate Immune Factors.- The Effects of Colostrum on Neutrophil Function: Decreased Deformability with Increased Cytoskeleton-Associated Actin.- Peroxidases in Human Milk.- Lactoferrin Binding to Its Intestinal Receptor.- Free Fatty Acids and Monoglycerides: Anti-Infective Agents Produced During the Digestion of Milk Fat by the Newborn.- The Role of Milk-Derived Antimicrobial Lipids as Antiviral and Antibacterial Agents.- Anti-Adhesive Molecules in Human Milk.- The Effect of Human Milk on the Adherence of Enterohemorrhagic E. Coli to Rabbit Intestinal Cells.- Session V: Specific Immune Factors.- Identification and Use of Protective Monoclonal IgA Antibodies Against Viral and Bacterial Pathogens.- Production and Use of Monoclonal IgA Antibodies Complexed with Recombinant Secretory Component for Passive Mucosal Protection.- Epithelial Transport of IgA Immune Complexes.- Association of Human Milk SIgA Antibodies with Maternal Intestinal Exposure to Microbial Antigens.- Serum and Breast Milk Antibodies to Food Antigens In African Mothers And Relation To Their Diet.- Modulation of the Immune Response by Maternal Antibody.- Maternal Determinants of Neonatal Immune Response: Effect of Anti-Idiotype in the Neonate.- Immunoglobulin G Subclasses in Human Colostrum and Milk.- Secretory Defenses Against Giardia Lamblia.- Session VI: Antiviral Immunity.- Epidemiological Perspective of Breastfeeding and Acute Respiratory Illnesses in Infants.- Serotypes of Rotavirus That Infect Infants Symptomatically and Asymptomatically.- Immune Response to Rotavirus Vaccines Among Breast-FED and Nonbreast-FED Children.- Recent Advances in Development of a Rotavirus Vaccine for Prevention of Severe Diarrheal Illness of Infants and Young Chiuldren.- Rotavirus Specific Breast Milk Antibody in Two Populations and Possible Correlates of Protection.- Human Milk and HIV Infection: Epidermiologic and Laboratory Data.- Characterization of a Human Milk Factor That Inhibits Binding of HIV GP120 to Its CD4 Receptor.- Breast Milk Transmission of Cytomegalovirus (CMV) Infection.- Antibody Responses to Cytomegalovirus in Serum and Milk of Newly Delivered Mothers.- Protection of Neonatal Mice from Fatal Reovirus Infection by Immune Serum and Gut Derived Lymphocytes.- Passive Immune Protection from Diarrhea Caused by Rotavirus or E. Coli: an Animal Model to Demonstrate and Quantitate Efficacy.- Session VII: Antibacterial Immunity.- The Antibody Response in Infants after Colonization of the Intestine with E. Coli O83. Artificial Colonization Used as a Prevention Against Nosocomial Infections.- Antibodies to Streptococci Pneumoniae in Sera and Secretions of Mothers and Their Infants.- T...